MyBioSource.com's TARBP2 Antibody (N-term) is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: ELISA, Immunohistochemistry, and Western Blot. The TARBP2 Antibody (N-term) was generated using TARBP2, and TRBP2 as the antigen and it reacts with Human, Mouse, Rat, and Xenopus/Amphibian.
Description
HIV-1, the causative agent of acquired immunodeficiency
syndrome (AIDS), contains an RNA genome that produces a
chromosomally integrated DNA during the replicative cycle.
Activation of HIV-1 gene expression by the transactivator Tat is
dependent on an RNA regulatory element (TAR) located downstream of
the transcription initiation site. The protein encoded by this gene
binds between the bulge and the loop of the HIV-1 TAR RNA
regulatory element and activates HIV-1 gene expression in synergy
with the viral Tat protein. Alternative splicing results in
multiple transcript variants encoding different isoforms. This gene
also has a pseudogene